Scientists are studying a new way to help stop Lyme disease on Nantucket Island. The plan is to use gene-editing technology to create mice that cannot spread the bacteria which cause the illness. The proposal comes from researchers at MIT, who believe that controlling the mice population could break the cycle of Lyme disease.
Lyme disease is a major health problem on Nantucket. Every year, many residents and visitors are infected. Symptoms often start with fever, fatigue, and a rash, but the disease can also cause long-term joint pain, heart problems, and nerve damage if not treated early. Studies suggest that about 15% of the island’s people have been affected at some point.
The main carriers of the bacteria are white-footed mice. When ticks bite these mice, they pick up the bacteria and then pass it on to humans. While deer are often linked with Lyme disease, experts say the true source is the infected mice.
To fight this, scientists plan to use CRISPR, a powerful gene-editing tool. They would give the mice a special antibody gene that makes them resistant to Lyme bacteria. Once these genetically engineered mice reproduce, their offspring would also carry the protective trait. Over time, more and more mice on the island would be unable to spread Lyme disease to ticks.
The research team suggests releasing the modified mice during the winter, when wild mouse numbers are lowest. They also want to test the idea on a smaller island before making any changes on Nantucket.
Not everyone is comfortable with the plan. Some residents worry about possible effects on the local environment. Mice are an important food source for hawks, owls, and other animals. Scientists agree that careful testing, strict safety checks, and community approval are needed before moving forward.
If the project works, it could not only help Nantucket but also provide a model for reducing Lyme disease in other parts of the United States.
